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Teniposide
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型号:29767-20-2

更新时间:2024-05-23  |  阅读:535

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仅用于工业应用或科学研究,不可用于人类或动物的临床诊断或治疗,非药用.Teniposide is a semisynthetic derivative of podophyllotoxin with antineoplastic activity. Teniposide forms a ternary complex with the enzyme topoisomerase II and DNA, resulting in dose-dependent single- and double-stranded breaks in DNA, DNA: protein cross-links, inhibition of DNA strand religation, and cytotoxicity. This agent acts in the late S or early G phase of the cell cycle.
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