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Bosutinib
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型号:380843-75-4

更新时间:2024-05-23  |  阅读:533

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仅用于工业应用或科学研究,不可用于人类或动物的临床诊断或治疗,非药用.Bosutinib is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy
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