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Lopinavir
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型号:192725-17-0

更新时间:2024-05-23  |  阅读:5634

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仅用于工业应用或科学研究,不可用于人类或动物的临床诊断或治疗,非药用.Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[1][2]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM
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